Peptide

BPC-157

The body's repair signal

Body Protection Compound-157 is a synthetic peptide derived from a protective protein found in gastric juice. It has shown remarkable regenerative properties in various tissues including tendons, ligaments, muscles, and the gastrointestinal tract.

Mechanisms

Angiogenesis promotion
Nitric oxide modulation
Growth hormone receptor upregulation
VEGF stimulation
Anti-inflammatory pathways

Dosing

Typical dose

250–500mcg

Timing

Administer subcutaneously near injury site or systemically. Can be split into AM/PM doses.

Synergies

TB-500

BPC-157 and TB-500 work through complementary pathways for tissue repair

Strong

GHK-Cu

BPC-157 enhances GHK-Cu's tissue remodeling effects

Moderate

KPV

BPC-157 and KPV synergize for gut healing protocols

Strong

LL-37

BPC-157 and LL-37 support tissue repair and infection defense

Moderate

Research

Review2018

Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease

Sikiric P et al·Current Pharmaceutical Design

BPC-157 demonstrated significant healing effects on various GI lesions including IBD models with anti-inflammatory mechanisms

Animal study2014

Pentadecapeptide BPC 157 enhances the growth hormone receptor expression

Chang CH et al·Life Sciences

BPC-157 upregulates GH receptor expression suggesting mechanism for systemic regenerative effects