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Supplement

Apigenin

CD38 inhibitor for NAD+

A flavonoid that inhibits CD38 enzyme, preserving NAD+ levels. Supports sleep and cellular health through multiple pathways.

Mechanisms

  • CD38 inhibition
  • NAD+ preservation
  • Sleep support
  • Anxiolytic

Dosing

Typical dose

50–100mg

Timing

Evening dosing for sleep. Synergistic with NAD+ precursors.

Synergies

NMN (Nicotinamide Mononucleotide)

NMN and Apigenin support NAD+ through synthesis and preservation

Strong
Melatonin

Melatonin and Apigenin support sleep through complementary mechanisms

Moderate