stillwork
Supplement

Fisetin

Potent senolytic

A flavonoid showing strong senolytic activity in research. May help clear senescent cells and support healthy aging.

Mechanisms

  • Senolytic activity
  • Antioxidant
  • Neuroprotection
  • Anti-inflammatory

Dosing

Typical dose

100–500mg

Timing

Intermittent high-dose protocols for senolytic effect. Liposomal forms.

Synergies

Quercetin

Quercetin and Fisetin provide synergistic senolytic effects

Strong
Spermidine

Spermidine and Fisetin both promote autophagy and cellular cleanup

Moderate

Research

Animal study2018

Fisetin is a senotherapeutic that extends health and lifespan

Yousefzadeh MJ et al·EBioMedicine

Fisetin reduced senescence markers and extended healthspan in aged mice